Cornelia De Lange

The Behavioural Phenotype of Cornelia de Lange Syndrome

Presenter: Prof. Chris Oliver

Date of presentation: 6th November, 2017

Conference or event: The seventh European course in clinical dysmorphology: “What I know best.”

Venue: Universita Cattolica del Sacro Cuore, Rome


Overview of the talk

The presentation focused on Cornelia de Lange syndrome in children and adults. The two prominent issues of self-injurious behaviour and the social and cognitive phenotype were discussed in detail with reference to the published literature. The content of the presentations draws attention to the importance of describing the underlying cognitive and social endophenotypes that underpin behavioural difference and the importance of describing the developmental trajectory. Self-injury and autism are described and the ways in which people with CdLS think are shown to be related to some features of autism.



Book chapters, accessible summaries or overviews

Overviews and models of behavioural difference in CdLS

Self-injurious behaviour in CdLS

Autism spectrum phenomenology in CdLS

Social behaviour in CdLS

Cognitive profiles in CdLS

Age related changes in CdLS

Anxiety in CdLS


Relevant lectures available online

Published research on CdLS by members of the Cerebra Centre for Neurodevelopmental Disorders: Prof. Chris Oliver


For an overview of CdLS click here

Go Back